Microvascular density and hypoxia-inducible factor in intraepithelial vocal fold lesions
نویسندگان
چکیده
منابع مشابه
Single injection of basic fibroblast growth factor to treat severe vocal fold lesions and vocal fold paralysis.
OBJECTIVES/HYPOTHESIS Severe vocal fold lesions such as vocal fold sulcus, scars, and atrophy induce a communication disorder due to severe hoarseness, but a treatment has not been established. Basic fibroblast growth factor (bFGF) therapies by either four-time repeated local injections or regenerative surgery for vocal fold scar and sulcus have previously been reported, and favorable outcomes ...
متن کاملRadiophonosurgery of benign superficial vocal fold lesions.
OBJECTIVE To conduct a prospective randomized controlled trial describing and investigating the efficacy and safety of radiosurgical excision of benign superficial vocal fold lesions. MATERIALS AND METHODS Fifty patients with benign superficial vocal fold lesions (20 vocal nodules, 27 vocal polyps and three Reinke's oedema) who failed conservative therapy were included in the study. They were...
متن کاملGender and age in benign vocal fold lesions.
OBJECTIVE/HYPOTHESIS Certain lesions appear to occur predominantly in one gender or in younger or older patients. We examined a large sample from a treatment-seeking population to describe gender and age associations of an array of benign vocal fold lesions. STUDY DESIGN Retrospective review. METHODS The medical records and evaluations of all adult patients presenting for care over a 5-year...
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Naïve T cells activated by antigen-presenting cells (APC) can be differentiated into at least four major types of T-helper (T(H)) cells: T(H)1, T(H)2, T(H)17 and inducible regulatory T cells (iTreg) based on their unique cytokine production profiles and characteristic functions.(1) T(H)1 produce interferon-γ (IFNγ) and are important for protective immune responses to intracellular viral, bacter...
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cell metabolism. Cells respond to decreased oxygen tension by inducing adaptive responses aimed at restoring oxygen availability and maintaining energy balance. Most responses to hypoxia are mediated by the activation of a family of transcription factors termed hypoxia-inducible factors (HIF). HIF have been shown to regulate vascular endothelial growth factor (VEGF) produced by hypoxic cells (s...
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ژورنال
عنوان ژورنال: European Archives of Oto-Rhino-Laryngology
سال: 2019
ISSN: 0937-4477,1434-4726
DOI: 10.1007/s00405-019-05355-2